Vanadium distribution in rats and DNA cleavage by vanadyl complex: implication for vanadium toxicity and biological effects.

Vanadium distribution in rats and DNA cleavage by vanadyl complex: implication for vanadium toxicity and biological effects.

Vanadium ion is toxic to animals. However, vanadium is also an agent used for chemoprotection against cancers in animals. To understand both the toxic and beneficial effects we studied vanadium distribution in rats. Accumulation of vanadium in the liver nuclei of rats given low doses of compounds in the +4 or +5 oxidation state was greater than in the liver nuclei of rats given high doses of va...

DNA binding, DNA cleavage and BSA interaction of Vanadium-Morin complex

Several oxovanadium(V) complexes have been shown as a potent anticancer agents. In view of the importance of Vanadium complexes a new Vanadium – Morin complex was synthesized and comprehensively characterized. To provide an insight on the mode and affinity of the interaction of these complex with calf thymus (CT) DNA the following experiments were carried out: fluorescence spectroscopy, UV–vis ...

The chemistry and biochemistry of vanadium and the biological activities exerted by vanadium compounds.

6.1.2. Aqueous V(III) Chemistry 877 6.1.3. Oxidation State of Vanadium in Tunicates 878 6.1.4. Uptake of Vanadate into Tunicates 879 6.1.5. Vanadium Binding Proteins: Vanabins 879 6.1.6. Model Complexes and Their Chemistry 880 6.1.7. Catechol-Based Model Chemistry 880 6.1.8. Vanadium Sulfate Complexes 881 6.2. Fan Worm Pseudopotamilla occelata 883 7. Vanadium Nitrogenase 883 7.1. Nitrogenases 8...

Assessment of Vanadium Distribution In

Decarbonylative halogenation by a vanadium complex.

Metal-catalyzed halogenation of the C-H bond and decarbonylation of aldehyde are conventionally done in nature. However, metal-mediated decarbonylative halogenation is unknown. We have developed the first metal-mediated decarbonylative halogenation reaction starting from the divanadium oxoperoxo complex K3V(5+)2(O2(2-))4(O(2-))2(μ-OH) (1). A concerted decarbonylative halogenation reaction was p...